大鼠早期缺血心肌中Basigin mRNA的表达

目的检测Basigin mRNA在大鼠早期缺血心肌和非缺血区心肌中的表达差异及探讨其法医学意义。方法建立大鼠早期心肌缺血手术模型,分为EIM组、NIM组、假手术组以及空白对照组,采用real-time PCR方法检测大鼠心肌缺血后15min、30min、1h和2h Basigin mRNA的表达量。结果与NIM组、假手术组及空白组相比,EIM组BSG mRNA表达量在缺血15min时降低,而冠状动脉结扎1h后表达量降低到SO组的一半,此时具有统计学差异(P0.05),结扎2h后表达量恢复至SO组水平。NIM组、SO组和空白对照组之间表达量无统计学差异(P0.05)。结论心肌急性缺血2小时内BSG mRNA表达降低明显,之后升高,说明BSG参与早期缺血心肌自我保护病理生理过程,提示BSG可用于鉴定早期心肌缺血。     

Examining the Impact of Early Childhood School Investments on Neighborhood Crime

This study tested the hypothesis that investments in early childhood schools have short-term crime reducing effects in neighborhoods. Time series data from the city of Tulsa, Oklahoma, were analyzed to evaluate the effects of an early childhood school built in the neighborhood of Kendall-Whittier as part of a larger neighborhood revitalization plan, on violent and property crime. Results revealed that after controlling for city-wide crime trends and monthly fluctuations, violent crime declined significantly in Kendall-Whittier. Further analysis indicated that the possible crime-reducing effects of school investments on violent crime spread beyond Kendall-Whittier, and no displacement was found. The results for property crime were mixed. The study demonstrates the use of clustering analysis, a useful tool in neighborhood-level research to identify comparison neighborhoods. The findings shed light on the possibility that investments in early childhood schools can yield results in a shorter term than anticipated, making them a desirable component of urban revitalization.     

珠江上游农业区域生态现状及生态安全预警系统的可行性研究

珠江上游地区农业人口众多 ,对生态环境依赖和压力很大。本文通过对珠江上游农业区域的生态现状进行综述 ,阐明生态安全对可持续发展的重要性以及生态安全预警系统建立的必要性 ,进而对建立生态安全预警系统的可行性、原则、基本方法和步骤进行初步研究 ,为这一区域生态环境和可持续发展研究奠定基础。     

国际关系对宪法发展的影响及其最新动态

国际关系是宪法运作的外部环境 ,国际关系的发展成为宪法发展的一个重要因素。考察近代宪法产生以来的国际关系与宪法发展的联系 ,可以明晰世界范围内宪法产生、发展的脉络 ,也将有助于把握未来宪法发展的最新动态     

EARLY INTERVENTION IN NEW ZEALAND FAMILY COURT CASES

In April 2010 the New Zealand Family Court introduced the National Early Intervention Process (NEIP) to diversify its previous unitary dispute resolution pathway into two tracks (standard and urgent). A “triage” model is now in use to assess and assign cases appropriately. This article outlines the key milestones in the Family Court's 30‐year history which have led to this new initiative to reduce delays and help avoid the escalation of family conflicts over the care of children into bitter and intractable disputes. NEIP represents the most overarching reform of the Family Court since the Court's inception in 1981.     

建立警察公共关系危机预警机制的构想

警察组织工作的特殊性,使得警察公共关系危机处于一种潜伏的状态,且成为一种社会常态,而各领域各层次的问题错综交织,都有可能成为公关危机发生的导火索,警察组织一味被动地应对警察公共关系危机只会使得警察组织公关更加被动。预防管理理论告诉我们：预防是战胜危机的第一法宝。科学构建中国特色警察公共关系危机的预警机制,是时代发展的呼...     

Lone Actor Terrorist Attack Planning and Preparation: A Data‐Driven Analysis,

This article provides an in‐depth assessment of lone actor terrorists’ attack planning and preparation. A codebook of 198 variables related to different aspects of pre‐attack behavior is applied to a sample of 55 lone actor terrorists. Data were drawn from open‐source materials and complemented where possible with primary sources. Most lone actors are not highly lethal or surreptitious attackers. They are generally poor at maintaining operational security, leak their motivations and capabilities in numerous ways, and generally do so months and even years before an attack. Moreover, the “loneness” thought to define this type of terrorism is generally absent; most lone actors uphold social ties that are crucial to their adoption and maintenance of the motivation and capability to commit terrorist violence. The results offer concrete input for those working to detect and prevent this form of terrorism and argue for a re‐evaluation of the “lone actor” concept.     

The cost of educating children: The accounts of a nineteenth century girls' boarding school in Orléans,France

Using a collection of 73 bills of a boarding school in Orléans (France), the article examines the cost of educating a child at the end of the nineteenth century. These bills concern the four daughters of a family from the Brittany nobility who each spent about 12 years at boarding school. Items on the bills reveal details of the daily life of the young girls through general boarding expenses, education costs, private lessons, clothing, medicine, and trips home for the holidays. Aspects of the family life of the girls and the boarding school (meals, religious instruction, health, and welfare) are described.     

Physical stature and biological living standards of girls and young women in the Netherlands,born between 1815 and 1865

This is the first study in Dutch anthropometric historiography that describes and analyzes the development of the biological standard of living of girls and young women from the perspective of female adult stature. It is shown that adult stature of women, imprisoned in the second half of the nineteenth century and born between 1815 and 1865, slightly increased, approximately 1cm. From 1850 onwards stature of women born in the cities notably increased. Development of female adult stature was compared to that of male stature; both were quite similar. No circumstantial evidence was found that girls or young women were on a disadvantage with respect to nutrition and (medical) care.     

Contextualising the ‘Responsibility to Protect’ in Darfur

ABSTRACT

This article argues for a thorough contextual analysis based on understanding local, regional and international politico-economic linkages in the Sudan, in order to ground prospects of the ‘Responsibility to Protect’ (R2P) doctrine in the ongoing crisis in Darfur. The R2P framework was crystallised by the International Commission on Intervention and State Sovereignty (ICISS) in 2001. It was adapted and subsequently endorsed by United Nations (UN) member states during the 2005 UN World Summit. The R2P ostensibly provides normative benchmarks on how states should respond to the quadruple human rights violations of genocide, war crimes, crimes against humanity and ethnic cleansing. Indeed, there is debate on whether the prevailing crisis in Darfur constitutes a test case for the application of the R2P. However, such debate is misplaced on two grounds: first, it glosses over the inherent conceptual deficiencies of the R2P, as presently constituted. More importantly, such debate is primarily inspired by reactionary and externalising influences based on past international failings, like Rwanda (1994) and Bosnia (1993). Hence, it is argued that the starting point of analysing the Darfur crisis should be a thorough investigation of how local, regional and international politico-economic factors have historically worked in an orchestrated fashion to trigger and sustain the crisis in the Sudan. Knowledge and an understanding of such historical specificity is a requisite for determining the relevance of the R2P in Darfur. The R2P, as presently constituted and practised, does not address this gap.